Human platelets contain brain-derived neurotrophic factor

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Human platelets contain brain-derived neurotrophic factor.

Neurotrophic support to peripheral sensory neurons is provided by 2 factors of related sequence, NGF and brain-derived neurotrophic factor (BDNF). NGF is present in peripheral target tissues, while BDNF has only been reported in the CNS. We now report the biological characterization and molecular cloning of a cDNA for BDNF from human platelets. BDNF in human platelets has biological activities ...

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Brain-derived neurotrophic factor:

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BACKGROUND Human milk contains a wide variety of nutrients that contribute to the fulfillment of its functions, which include the regulation of newborn development. However, few studies have investigated the concentrations of S100B protein, brain-derived neurotrophic factor (BDNF), and glial cell line-derived neurotrophic factor (GDNF) in human milk. The associations of the concentrations of S1...

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ژورنال

عنوان ژورنال: The Journal of Neuroscience

سال: 1990

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.10-11-03469.1990